METHOD OF SYNTHESIS OF 11-KETOSTEROID DERIVATIVE Russian patent published in 1998 - IPC

Abstract RU 2108340 C1

FIELD: chemical technology, steroids. SUBSTANCE: invention relates to new method of synthesis of 11-ketosteroid derivatives of the general formula (I) where: R - H, C1-C8-acyl, RI - CH3, CH2ORII; RII - H, -C1-C8-acyl and 3-oxo-group is protected as ethylenedithioketal. Compound of the formula (II) is converted to halogenhydrin of the formula (III) in the presence of alcohol and obtained product is treated with acid. EFFECT: improved method of synthesis. 7 cl

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RU 2 108 340 C1

Authors

Fransi Brion[Fr]

Zhan Bjuandia[Fr]

Kristian Diolez[Fr]

Mishel' Viva[Fr]

Dates

1998-04-10Published

1993-04-21Filed