AMINO ACID DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE BASIC SALTS THEREOF METHODS OF PREPARING AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY Russian patent published in 1998 - IPC

Abstract RU 2109731 C1

FIELD: chemical industry and pharmaceutical industry. SUBSTANCE: present invention describes amino acid derivatives of formula I: wherein R1 is C1-C8 alkoxycarbonyl or group of formula: wherein R2 is C1-C8 alkyl; R3 is hydrogen, and R4 is hydroxy group or R3 and R4 in combination are oxo group; R5 is C1-C8 alkoxycarbonyl or C1-C8-alkylcarbamoyl; R6 and R7 in combination are trimethylene or tetramethylene; R8 is phenyl-C1-C8 alkoxycarbonyl, quinolylcarbonyl; R9 is C1-C8 alkyl, phenyl-C1-C8 alkyl, cyano-C1-C8 alkyl, carbamoyl-C1-C8 alkyl, C1-C8-alkyltyl-C1-C8 alkyl, carbamoyl-C1-C8 alkyl or pharmaceutically acceptable basic salts thereof and are used for prophylaxis or treatment of viral infections. They are prepared by well known methods. EFFECT: improved properties of the pharmaceutical composition. 19 cl, 1 tbl

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RU 2 109 731 C1

Authors

Dzhosef Armstrong Martin[Gb]

Garez Dzhon Tomas[Gb]

Dates

1998-04-27Published

1992-01-31Filed