FIELD: chemical industry. SUBSTANCE: described are acetic acid derivatives of formula I: 
wherein L, M, Q and T are as defined in claim 1. Compounds are useful for treatment or prophylaxis of diseases associated with binding of adhesive proteins with thrombicytes and also aggregation of thrombicytes and cell-cell adhesion. Compounds are prepared by detachment of protective groups in corresponding protected compounds or by conversion of cyan group into amidine group in corresponding nitriles. EFFECT: improved properties of the title compounds. 23 cl, 193 ex, 1 tbl
| Title |
Year |
Author |
Number |
| DERIVATIVES OF N-ACYL-α-AMINO ACID OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, SIMPLE ETHERS OR ESTERS, AMIDES OR HYDRATES AND COMPOSITION INHIBITING ADHESIVE PROTEINS BINDING WITH PLATELETS AND PLATELET AGGREGATION |
1992 |
- Leo Alig[Ch]
- Paul Khadvari[Ch]
- Marianne Khjurtseler[Ch]
- Marsel Mjuller[Ch]
- Beat Shtejner[Ch]
- Tomas Veller[Ch]
|
RU2097378C1 |
| CARBOXAMIDES, THEIR HYDRATES AND SOLVATES AND PHYSIOLOGICALLY COMPATIBLE SALTS |
1994 |
- Zhan Akermann
- David Banner
- Klaus Gubernator
- Kurt Khil'Pert
- Zherar Shmid
|
RU2125991C1 |
| ACETIC ACID DERIVATIVES OR HYDRATES THEREOF, OR SOLVATES THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF |
1991 |
- Leo Alig[Ch]
- Al'Brekht Ehdenkhofer[Ch]
- Marsel Mjuller[Ch]
- Arnold Tchetsiak[De]
- Tomas Ueller[Ch]
|
RU2072359C1 |
| SULFONEAMIDOCARBOXAMIDES, THEIR HYDRATES AND PHYSIOLOGICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION ON SAID |
1993 |
- Zhan Akermann
- David Banner
- Klaus Gubernator
- Kurt Khil'Pert
- Zherar Shmid
|
RU2133739C1 |
| METHOD OF SYNTHESIS OF CARBOXYLIC OR SULFONIC ACID AMIDES OR THEIR PHYSIOLOGICALLY COMPATIBLE SALTS |
1990 |
- Leo Alig[Ch]
- Albrekht Edenkhofer[Ch]
- Marsel Mjuller[Ch]
- Arnold Trtsekiak[De]
- Tomas Veller[Ch]
|
RU2072986C1 |
| DERIVATIVES OF ARYL- AND HETEROARYLSULFONEAMIDES AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1995 |
- Fol'Ker Broj
- Kaspar Burri
- Zhan-Mari Kassal'
- Martin Klozel'
- Zhorzh Khirt
- Bernd-Mikhaehl' Leffler
- Marsel' Mjuller
- Verner Najdkhart
- Khenri Ramuz
|
RU2163598C2 |
| DERIVATIVES OF THIAZOLE, METHOD OF THEIR SYNTHESIS, COMPOSITION BASED ON THEREOF AND INTERMEDIATE COMPOUND |
1999 |
- Leo Alig
- Al'Brekht Ehdenkhofer
- Kurt Khil'Pert
- Tomas Veller
|
RU2166503C2 |
| CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL AGENT |
1994 |
- Peter Angern
- Chung-Chen Vej
|
RU2130939C1 |
| WATER-SOLUBLE DERIVATIVES OF PHENYLGLYCINE |
2003 |
- Alig Leo
- Grebke Tsbinden Katrin
- Obst Ul'Rike
|
RU2283305C2 |
| OXAZOLIDEN-1-ONE DERIVATIVES, AND DRUG BASED THEREON |
1994 |
- Janos Borgulia
- Khans Bruderer
- Roland Jakob-Retne
- Stefan Rever
|
RU2133743C1 |
