2-AMINO-N- [4-(AMINOCARBONYL)PYRIMIDIN-2-YL] AMINO-ALKYL PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION Russian patent published in 1998 - IPC

Abstract RU 2111963 C1

FIELD: pharmaceutical industry. SUBSTANCE: present invention describes compounds of general formula I given in the specification wherein m is 0 or 1, R1 is methyl group, R2 is phenoxy C1-C4 alkyl group or R1 and R2 form together, and with nitrogen atom attached to them, 4- phenoxypiperidin -1-yl group, phenoxymethylpiperidin-1-yl group or 4-phenyl piperazin - 1-yl group, and R3 is hydrogen atom, and only when n is 1, hydroxy group or methoxy group. EFFECT: improved properties of the pharmaceutical composition. 7 cl, 2 tbl

Similar patents RU2111963C1

Title Year Author Number
DERIVATIVES OF 2-AMINOPYRAZINE-5-CARBOXAMIDE, A METHOD OF THEIR SYNTHESIS AND A DRUG AND A PHARMACEUTICAL COMPOSITION CONTAINING SAID 1994
  • Paskal' Zhorzh
  • Benua Marabu
  • Zhak Fruasan
RU2128176C1
3-SUBSTITUTED DERIVATIVES OF 3,4,5,6,7,8-HEXAHYDRO-PYRIDO-[4',3':4,5]-THIENO[2,3- D]-PYRIMIDINE 1997
  • Shtajner Gerd
  • Bish Vil'Frid
  • Bakh Al'Fred
  • Ehmling Frants
  • Vike Karsten
  • Teshendorf Khans-Jurgen
  • Bel' Bertol'D
  • Kerrigan Frank
  • Chitkhem Sharon
RU2198888C2
DERIVATIVES OF 1H-PYRIDO[3,4-B]INDOLE-4-CARBOXAMIDE, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1997
  • Ehvanno Jannik
  • Sevren Mirej
  • Maluazel' Kristian
  • Legalludek Odett
  • Zhorzh Paskal'
RU2180904C2
PYRAZOLO[1,5-a]PYRIMIDINE AND THIENO[3,2-b]PYRIMIDINE DERIVATIVES AS MODULATORS OF IRAK-4 2011
  • Arora Nidkhi
  • Chen Shaotsin
  • Germann Jokhannes Kornelius
  • Kuglstatter Andreas
  • Labadi Sharada Shenvi
  • Lin Klara Jeu Jen
  • Lukas Metju K.
  • Mor Emi Dzheraldin
  • Papp Eva
  • Talamas Fransisko Ksaver
  • Vanner Jutta
  • Chzhaj Tszanshen
RU2604062C2
DERIVATIVES OF 5-PHENYL-3-(PIPERIDINE-4-YL)-1,3,4-OXADIAZOLE- -2(3H)-ONE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND DRUG 1996
  • Zhegam Samir
  • Lokkhed Alister
  • Galli Frederik
  • Nedelek Alen
  • Solin'Jak Aksel'
  • De Krju Lorans
RU2167160C2
DERIVATIVES OF BENZO-[C]-PHENANTHRIDINIUM, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION 1992
  • Kristian Oornaert[Be]
  • Mark Doma[Fr]
  • Mishel' Aletrju[Fr]
  • Zhan-Klod Mjuller[Fr]
RU2073675C1
DERIVATIVES OF N-(3-AMINOPROPYL)-N-PHENYL-5,6,7,8-TETRAHYDRO- -NAPHTHALENE-2-CARBOXAMIDE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION 1995
  • Zhorzh Paskal'
  • Frost Dzhonatan
  • Paso Patrik
  • Russel' Korinn
  • Barch Rezhin
  • Vil'Jams Pol Khauard
  • Mjuller Zhan-Klod
RU2138479C1
DERIVATIVES OF QUINOLINE-2(1H)-ONE, METHODS OF THEIR SYNTHESIS, DRUG AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1996
  • Mak Kor Gari
  • Khornar Kristian
  • Dellak Zhenev'Ev
  • Aletrju Mishel'
RU2167874C2
AMINES FOR PREPARING MEDICINAL AGENTS DESIGNATED FOR PROPHYLAXIS OF TUMOR CELLS PROLIFERATION 1997
  • Brel'Er Zhan-Klod
  • Ferrara Paskual'
  • Lebuteje Kristin
  • Pol' Rajmon
  • Rozenfel'D Khorkhe
  • Van Bruk Did'E
RU2176502C2
4-PHENOXY-NICOTANIMIDES OR 4-PHENOXY-PYRIMIDINE-5-CARBOXAMIDES 2011
  • Bissants Katerina
  • Demlou Genrietta
  • Ehrikson Shon Dehvid
  • Kim Kujudzhin
  • Martin Rajner E.
  • Obst Zander Ul'Rike
  • P'Etraniko-Kol' Sherri Linn
  • Rikhter Khans
  • Ull'Mer Kristof
RU2565077C2

RU 2 111 963 C1

Authors

Paskal' Zhorzh[Be]

Benua Marabu[Fr]

Zhak Fruassan[Fr]

Zhan P'Er Merli[Fr]

Dates

1998-05-27Published

1993-07-02Filed