DERIVATIVES OF 1H-PYRIDO[3,4-B]INDOLE-4-CARBOXAMIDE, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2002 - IPC

FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to compounds of the general formula (I): where X means hydrogen or halogen atom or alkyl, alkoxyl, trifluoromethyl or phenylmethoxy-group; R₁ means hydrogen atom or alkyl, cyclopropyl or phenylmethyl group; R₂ means either alkyl group that can be substituted, or phenylalkyl group that can be substituted, or cyclohexylmethyl group, or thienylmethyl group, or pyridinylmethyl group, or phenyl group that can be substituted, or pyridinyl-group, or 5-methyl-1,2-oxazolyl-group, or 5-methyl-1,3,4-thiadizolyl- -group, or naphthalenyl-group; R₃ and R₄ each means hydrogen atom or alkyl, 2-methoxyethyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl or phenylalkyl group or in common with nitrogen atom that carries these groups they form either pyrrolidinyl-group that can be substituted, or piperidinyl-group, or morpholinyl-group, or 4-methylpiperazinyl-group, or azethidinyl-group, or thiazolidinyl-group and a bond between carbon atoms at positions 3 and 4 is a single or double one. Invention can be used in therapy. EFFECT: improved method of synthesis, valuable medicinal properties. 9 cl, 2 tbl