DERIVATIVES OF METHYLPIPERAZINE-AZEPINE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 1998 - IPC

FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: derivatives of methylpiperazine-azepine of the formula (I) given in description where X - O, S, Se, NH or NR₃ where R₃ - , or C₁-C₄-alkyl; R₁, R₂ - H, halogen or C₁-C₄-alkyl; N₁ is benzene ring and N₂ is pyridine heterocycle, or vice versus, where nitrogen atom of pyridine ring is at position b, b′,, d or d′ at condition that if R₁ and R₂ are H and X - S, O or NH then N₁ is pyridine ring and N₂ - benzene ring being pyridine nitrogen can not be at position d′; or N₁ and N₂ are both - pyridine rings with nitrogen atom at position b and d′ when X - S and R₁ and R₂ - H, or their salts. Synthesized compounds exhibit activity with respect to central nervous system. EFFECT: improved method of synthesis. 5 cl, 1 tbl