FIELD: biotechnology. SUBSTANCE: porous collagen-containing material to be frozen preliminary is thawed out, treated with an alkaline agent aqueous solution at pH 10-12 and 0.1-1.0-% formaldehyde solution, washed out to neutral medium reaction, pressed out nonbound moisture and dried at 20-60 C. If necessary, before final drying material is impregnated with solution of medicinal and/or antiseptic agent and pressing at 40-100 kg/cm2. EFFECT: improved method of preparing, improved quality of material, broadened pattern of the porous collagen-containing materials. 2 cl, 10 ex
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