FIELD: organic chemistry. SUBSTANCE: invention relates to derivatives of decahydroisoquinoline of the formula (I) given in description exhibiting activity of antagonist of receptors of amino acid-mediating agent of excitement. Synthesized compounds can be used in medicine. Invention relates to pharmaceutical composition based on the compounds synthesized also. EFFECT: improved method of synthesis, enhanced effectiveness of compounds synthesized. 8 cl, 3 tbl, 26 ex
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Year |
Author |
Number |
| METHOD OF TRICYCLE COMPOUNDS SYNTHESIS |
1991 |
|
RU2007401C1 |
| DERIVATIVES OF AMINOBICYCLO[3,1,0]HEXANE-2,6-DICARBOXYLIC ACID AND PHARMACEUTICAL COMPOSITION |
1995 |
- Khelton Dehvid Rid
- Monn Dzhejms Allen
- Robi Rodzher Levis
- Shopp Dehrril Darvin
- Tizzano Dzhozef Patrik
|
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| CIS-(-)-4-[(1(2)H-TETRAZOLE-5-YL)-METHYL]-2-PIPERIDINE CARBOXYLIC ACID AND PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY AS AN ANTAGONIST OF EXCITEMENT AMINO ACID RECEPTORS |
1991 |
|
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| TRIPEPTIDE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES, PHARMACEUTICAL COMPOSITION SHOWING INHIBITING ACTIVITY WITH RESPECT TO THROMBIN AMIDASE |
1994 |
- Pol Dehvid Gezellchen[Us]
- Robert Teodor Shuman[Us]
|
RU2105010C1 |
| PROCESS FOR PREPARING TETRAZOLE DERIVATIVES |
1989 |
|
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1993 |
- Robert Dzhon Ternanski[Us]
|
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1992 |
- Robert Dzhon Ternanski[Us]
|
RU2104280C1 |
| METHOD OF SYNTHESIS OF (S)--1÷1-N,N-DIMETHYL-3-(1-NAPHTHALINYL- -HYDROXY)-3-(2-THIENYL)-PROPANEAMINE AND (S)-±-N,N-DIMETHYL- -3-(1-NAPHTHALINYLHYDROXY)-3-(2-THIENYL)-PROPANEAMINE PHOSPHATE |
1994 |
|
RU2127269C1 |
| PEPTIDE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF THROMBIN INHIBITION IN MAMMAL |
1995 |
- Smit Dzheral'D Flojd
- Uili Majkl Robert
- Shakht Aaron Lejg
- Shuman Robert Teodor
|
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| BENZO-[F]-QUINOLINONES, METHOD OF INHIBITION, METHOD OF SYNTHESIS OF BENZO-[F]-QUINOLINONES, METHOD OF RACEMATES SPLITTING AND DI-P-TOLUOYL-(D)- OR (L)-TARTARIC ACID SALT |
1992 |
- Dzhejms Ehdmund Odia
- Kennet Stiven Kherch
- Charl'Z Dehvid Dzhons
- Dehvid Ehrnst Lokhorn
- Loretta Ehms Makkuajd
|
RU2126386C1 |
