PHARMACEUTICAL PREPARATION CONTAINING GROWTH HORMONE OR GROWTH HORMONE DERIVATIVE AND HISTIDINE OR HISTIDINE DERIVATIVE, A PREPARATION THAT IS GROWTH HORMONE CRYSTALS CONTAINING HISTIDINE OR HISTIDINE DERIVATIVE AND A METHOD OF PREPARING GROWTH HORMONE CRYSTALS AND HISTIDINE OR HISTIDINE DERIVATIVE Russian patent published in 1998 - IPC

FIELD: medicine, pharmacy. SUBSTANCE: pharmaceutical preparation containing growth hormone and histidine or histidine derivative as an addition or a buffer substance shows very high resistance to deamidination, oxidation and peptide bonds cleavage. Product stability provides a possibility of its storage and transport in a lyophilized state or in the form of dissolved or again dissolved preparation at environment temperature. Crystallization of growth hormone in the presence of histidine or its derivative provides the increased crystals yield. EFFECT: increased yield, improved purity of growth hormone. 14 cl, 12 tbl, 2 dwg, 11 ex