FIELD: medicine. SUBSTANCE: method involves treating the biological fluid with polyethylene glycole-6000 before introducing it into analysis test system containing antibodies specific with respect to the antigen to be detected. Immune complexes containing antigen sought for and autologic antibodies are separated from the system in this way. Circulating redundant autologic antibodies are removed. Resuspension of sedimented immune complexes being done in initial volume, the complexes are subjected to dissociation and the antigen becomes easily accessible for antibodies included in the analysis test system. EFFECT: simplified and accurate diagnosis method.
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Authors
Dates
1999-01-10—Published
1995-01-11—Filed