FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of thioformamide of the general formula (I) where Y - a group of the formula -C(O)-, -CH(OH)-,
=N-O-Ph, O=C(Ph)-O
; Z means
; A means substituted or nonsubstituted imidazopyridyl; R1, R2, R3 and R4 - hydrogen or lower alkyl, or their pharmaceutically acceptable salts exhibiting high hypotensive properties. EFFECT: improved method of synthesis, enhanced pharmacological activity of compounds. 6 cl, 24 ex, 1 tbl
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Authors
Dates
1999-01-20—Published
1992-10-06—Filed