SEPARATION METHOD FOR FUCOSYLATED ANTIBODIES Russian patent published in 2018 - IPC C07K1/22 C07K14/705 C07K16/00 

Abstract RU 2650873 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, in particular to a method for isolating antibodies having varying degrees of fucosylation. Method is based on the affinity of binding of antibodies to the Fc receptor immobilized on the support. Fc receptor of the invention is FcγRIIIa (V158) with C-terminal labels (Lysine)6 and (Histidine)6.

EFFECT: present invention makes it possible to increase the efficiency of the isolation of antibodies having varying degrees of fucosylation.

22 cl, 8 dwg, 3 tbl, 5 ex

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RU 2 650 873 C2

Authors

Frajmozer-Grundshober Anna

Eger Kristian

Zondermann Peter

Umana Pablo

Dates

2018-04-17Published

2012-10-16Filed