FIELD: biotechnology.
SUBSTANCE: present invention relates to the field of biotechnology, in particular to a method for isolating antibodies having varying degrees of fucosylation. Method is based on the affinity of binding of antibodies to the Fc receptor immobilized on the support. Fc receptor of the invention is FcγRIIIa (V158) with C-terminal labels (Lysine)6 and (Histidine)6.
EFFECT: present invention makes it possible to increase the efficiency of the isolation of antibodies having varying degrees of fucosylation.
22 cl, 8 dwg, 3 tbl, 5 ex
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Authors
Dates
2018-04-17—Published
2012-10-16—Filed