DRUG USED IN CARDIAC FAILURE Russian patent published in 1999 - IPC

FIELD: medicine, pharmacy. SUBSTANCE: invention proposes drugs used in medicine for treatment of patients with cardiac failure which have as an active components at least one of compounds of the formula (I) or their pharmacologically acceptable salts where n = 0 or 1; A means hydroxyl-group or hydrogen atom; B means hydrogen atom; X means oxygen atom, nitrogen atom; R¹ and R² mean hydrogen atom, C₁-C₄-alkyl; R³ and R⁴ mean hydrogen atom, C₁-C₆-alkyl, C₂-C₆-alkenyl, or C(=Y)Z-R⁶ where Z is NH; Y is O, S, ≡ or they form together 1,4-butylene or 1,5-pentylene. These compounds show the enhanced activity with respect to cardiac muscle contractions and strong activity with respect to cardiac contraction rate decrease. EFFECT: enhanced effectiveness of compounds proposed. 5 cl, 6 tbl, 71 ex