SUBSTITUTED THIAZOLIDINEDIONE AND METHOD OF PREPARING THEREOF Russian patent published in 1999 - IPC

Abstract RU 2128179 C1

FIELD: medicine. SUBSTANCE: present invention describes maleic acid salt of 5-[4-[2-(N-methyl-N (2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione or isomeric or tantomeric form thereof and/or pharmaceutically acceptable solvate is prepared by reacting 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy] thiazolidine -2,4-dione with maleate ion source HOOC CH = CH COO-.. Compounds are more soluble in water, have good water stability and is useful for treating hyperton and cardio- vascular diseases. EFFECT: improved properties of the title compounds. 3 cl, 2 ex

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RU 2 128 179 C1

Authors

Kolin Ripli Pul

Robin Shervud Roman

Mal'Kol'M Dehvid Brajvell

Alan Uil'Jam Tremper

Dates

1999-03-27Published

1993-09-01Filed