METHOD OF TREATMENT OF STATE WHERE 5HT-LIKE AGONIST, DERIVATIVE OF TETRAHYDROCARBAZOLE IS REQUIRED, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY OF AGONIST OF 5HT-LIKE RECEPTORS Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention proposes compounds of the general formula (I): where R¹ means hydrogen, halogen atom, hydroxy-, nitro-, trifluoromethyl, C_1-6-alkoxy-, aryl-C_1-6-alkoxy-group, , C_1-6-alkanoylamino--(CH₂)_n- or C_1-6-alkylsulfonylamino--(CH₂)_n-group; R⁴ means hydrogen atom, C_1-6-alkyl or aryl-C_1-6-alkyl; R⁵ and R⁶ each independently means hydrogen atom or C_1-6-alkyl or R⁵ and R⁶ in common with nitrogen atom to which they are bound form a ring; n = 0, 1 or 2; R² and R³ each independently means hydrogen atom, C_1-6-alkyl or benzyl or in common with nitrogen atom to which they are bound form pyrrolidino-, piperidino- or hexahydroazepino-ring, or its physiologically acceptable salts that can be used for treatment of state, for example migraine, where 5-HT₁-like agonist is required. Also, invention describes new compounds of the formula (I), methods of their synthesis and pharmaceutical compositions containing thereof. EFFECT: improved methods of synthesis and treatment. 19 cl, 32 ex