FIELD: medicine. SUBSTANCE: isoquinolino [8,7,6-cd] in-dazol-6(2H)one, isoquinolino [5,6,7-cd] -6(2H)one or hydroxyl derivative thereof of general formula: C1-10 wherein R is hydrogen, one of X and Y is carbon atom, and the other is nitrogen atom; A and B are identical or different and are selected from group consisting of C2-10 alkyl or alkyl substituted by hydroxyl, or acid addition salt thereof. Compounds show antitumor activity. EFFECT: improved properties of the pharmaceutical composition. 12 cl, 4 dwg, 18 ex, 2 tbl
Title |
Year |
Author |
Number |
IMPROVED METHODS OF SYNTHESIS OF 6,9-BIS-[(2-AMINOETHYL)- -AMINO]BENZO[G]ISOQUINOLINE-5,10-DIONE MALEATE |
1995 |
- Sil'Vano Spinelli
- Roberto Didomeniko
|
RU2144028C1 |
6,9-BIS-(AMINOSUBSTITUTED)-BENZO[G]ISOQUINOLINE-5,10-DIONES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION ON THEIR BASIS, A METHOD OF TUMOR SUPPRESSION IN MAMMALS |
1992 |
|
RU2129546C1 |
DERIVATIVES OF BENZIMIDAZOLONE, MIXTURE OF THEIR ISOMERS OR THEIR ACID ADDITIVE SALTS AS ANTAGONIST OF RECEPTOR 5HT AND 5HT |
1992 |
- Dzhuzeppe Bietti[It]
- Franko Borsini[It]
- Mario Turkoni[It]
- Ehttore Dzhiral'Do[It]
- Mario Bignotti[It]
|
RU2096411C1 |
SULFONYL UREA AND RELATED COMPOUNDS AND USE THEREOF |
2016 |
- O'Nill Lyuk
- Koll Rebekka
- Kuper Mettyu
- Robertson Avril
- Shroder Kejt
|
RU2739356C2 |
METHOD OF SYNTHESIS OF PURE ENANTIOMERS OF 1,4-DIHYDROPYRIDINES, PURE ENANTIOMERS OF 1,4-DIHYDROPYRIDINES AND ISOTHIOUREIDES |
1990 |
- Karmelo A.Gandol'Fi[It]
- Marko Fridzherio[It]
- Karlo Riva[It]
- Andrea Tsal'Jani[It]
- Dzhordzho Long[It]
- Roberto Di Domeniko[It]
|
RU2069658C1 |
TRINUCLEAR CATIONIC PLATINUM COMPLEXES HAVING ANTITUMOR ACTIVITY, METHOD OF PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPLEXES |
1995 |
- Mariella Valsekki
- Marko Konti
- Luiza Del' Greko
- Karlo Bugatti
- Ehrnesto Menta
- Ferdinando Gil'Jani
- Karla Mantsotti
- Sil'Vano Spinelli
- Nikolas Farrell
|
RU2130941C1 |
TAXANE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT |
1994 |
- Ivao Odzima
- Ehtsio Bombardelli
|
RU2137764C1 |
N- (PHENYLSULPHONYL) BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS |
2017 |
- Wang, Shaomeng
- Chen, Jianyong
|
RU2744358C2 |
TETRAHYDROINDENOINDOLE COMPOUNDS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION SHOWING ANTIOXIDANT ACTIVITY, ANTIOXIDANT COMPOSITION AND A METHOD OF STABILIZATION OF COMPOUNDS EXHIBITING SENSITIVITY TO OXIDATION |
1990 |
- Malkol'M Sehjnsberi[Gb]
- Khovard Dzh.Shertser[Us]
|
RU2104270C1 |
N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS |
2017 |
- Wang, Shaomeng
- Chen, Jianyong
|
RU2722560C1 |