METHOD OF PREPARING 3-AZABICYCLO [3,3,1] NONANE DERIVATIVES Russian patent published in 1999 - IPC

FIELD: chemical industry. SUBSTANCE: new method of preparing new 3-azabicyclo [3,3,1] nonane derivatives of general formula I: wherein or м wherein n is 2,4 or 6 using Mannich reaction comprises reducing original КВН₄-dinitrobenzene with to 3,5- bis(acy-nitro)cyclohexene-1 dipotassium salt of formula A: . This salt is reacted with mixture of formaldehyde and primary amine, and the reaction solution is subsequently acidified with acetic acid to pH of 6 to prepare compounds of formula I wherein R is or is reacted with mixture of formaldehyde and diamine and the reaction solution is subsequently acidified with acetic acid to pH of 6 to prepare compounds of formula I wherein R is wherein n is 2,4 or 6. EFFECT: new compounds with valuable properties. 3 ex