FIELD: biotechnology. SUBSTANCE: biologically active substance has the natural and/or synthesized active components on the basis of bioactive components, filling agents or involuntary components. Bioactive components are collalytin and/or its components at weight content c1 and c2, respectively, and taken at the following limits: . Content of filling agents, accessory and random or involuntary components in the substance is homogenized to a value determined by ratio of the weight ratio c4 of nonhomogeneous residue to the weight content c5 of the completely homogenized components at the limits: 1 ≤ (c4+c5)/c5 ≤ 105. Ratio of minimal t1 and maximal t2 of hardness values distributed over the total surface of the substance provides at the limits: 1 ≤ (т1+αт2)/т2 ≤ 4 where α - an experimental coefficient at the limits: 0,4 ≤ α ≤ 3 and taken depending on the volume structure of substance and conditions of its final treatment. Biologically active substance is obtained by isolation of the preparation exhibiting collagenolytic activity from biological objects of marine origin or their elements in the presence of accessory additions. Biologically active components are separated from that to be used, purified and dried. Process of preparing the raw materials and the method of the substance preparing are optimized. EFFECT: improved method of preparing, broadened functional possibilities of the biologically active substance using, enhanced effectiveness of the substance consumption use in practice. 4 cl, 1 ex
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Authors
Dates
1999-07-10—Published
1998-10-13—Filed