FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new sulfoneamidocarboxamides of the general formula (I) where values A, Y, X are indicated in p. 1 of the invention claim. Also, the invention describes their hydrates and physiologically acceptable salts and a pharmaceutical composition based on compounds of the formula (I). Compounds and composition show an antiaggregate and anticoagulant activity and capability to inhibit amidolytic activity of thrombin. EFFECT: new compounds indicated above, valuable pharmacological properties of compounds. 17 cl, 2 tbl, 73 ex
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Authors
Dates
1999-07-27—Published
1993-03-04—Filed