USE OF 5-THIA-1,4-DIAZABICYCLO[4,2,0]OCTANE-3,8-DIOXODERIVATIVES IN ANTITUMOR THERAPY Russian patent published in 1999 - IPC

FIELD: organic chemistry, oncology, pharmacology. SUBSTANCE: invention relates to a new use of 5-thia-1,4-diazabicyclo[4,2,0]octane-3,8-dioxoderivatives of the general formula (I): where radicals have the following values: R¹ means hydrogen, halogen atom; R² means hydrogen, halogen atom, amino-group, PhCH₂CONH, PhOCH₂CONH, phthalimido-group, o-MeNHCOC₆H₄COOH, 3-chlorophenyl-5-methyloxazolyl-4-carbonylamino-group; R³ means hydrogen atom, alkyl, benzyl, heterocyclic ring, for example, isoxazole, pyrazole; n = 1 or 2. This compound shows an antitumor activity. EFFECT: broadened pattern of agents showing an antitumor effect. 1 test