POLYETHYLENE GLYCOL DERIVATIVE OF NEUROTROPHIC FACTOR POLYPEPTIDE AND METHOD OF PREPARATION THEREOF Russian patent published in 1999 - IPC

Abstract RU 2136694 C1

FIELD: biochemical syntheses. SUBSTANCE: compound is prepared by interaction of polypeptide selected from growth factor isolated from brain and neurotrophin-3 with polyethylene glycol under reductive alkylation conditions at acidic pH. Homogeneous conjugate molecules thus prepared bears directly attached polyethylene glycol residues. EFFECT: facilitated synthetic procedure. 14 cl, 8 dwg, 2 tbl, 11 ex

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RU 2 136 694 C1

Authors

Kinstler Olaf.F.

Jen K'Jao

Dates

1999-09-10Published

1995-11-13Filed