FIELD: medicinal industry, biotechnology. SUBSTANCE: method involves isolation of leukocytes, their suspending in nutrient medium, induction, biosynthesis of interferon and inactivation of the virus-inducer. For induction of leukocytes the cold-adapted Newcastle disease virus obtained by the successive up to 30 passages in developing chicken embryos at temperature below 35 C is used for increase of interferon yield and providing stable indices of the preparation activity. EFFECT: increased yield of interferon. 2 ex
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Authors
Dates
1999-10-27—Published
1998-07-06—Filed