5-NITRO-4-OXOPENTANOIC (5-NITROLEVULINIC) ACID ALKYL ESTERS AND METHOD OF THEIR SYNTHESIS Russian patent published in 1999 - IPC

Abstract RU 2141472 C1

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to 5-nitro- -4-oxopentanoic acid alkyl esters of the formula: O₂NCH ₂COCH₂CH₂COOR₁ where C₁-C₄ means R-alkyl and a method of their synthesis. These alkyl esters can be used for synthesis of biologically active substances of the broad spectrum, in part, 5-aminolevulinic acid and its alkyl esters used in photodiagnosis and photo-dynamic therapy of oncological diseases. EFFECT: improved method of synthesis. 2 cl, 2 ex

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RU 2 141 472 C1

Authors

Zolina N.V.

Luk'Janets E.A.

Samojlova G.E.

Tkach I.I.

Dates

1999-11-20—Published

1998-08-31—Filed