FIELD: antibiotics, pharmacy. SUBSTANCE: invention relates to new derivatives of erythromycin of the general formula (I) 
where values Z, R1, R2 are given in p. 1 of the invention claim. New derivatives of erythromycin show a bactericidal effect, in part, they show activity with respect to gram-positive and gram-negative bacteria. Invention describes also methods of their synthesis and a pharmaceutical composition based on compounds of the formula (I). EFFECT: improved method of synthesis of new erythromycin derivatives, valuable antibacterial properties. 12 cl, 20 ex
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Year |
Author |
Number |
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1995 |
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- Odil' Le Martre
|
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|
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1991 |
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|
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| BICYCLIC NITROGEN-CONTAINING DERIVATIVES OR THEIR SALTS WITH MINERAL AND ORGANIC ACIDS OR BASES, METHODS OF THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS |
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