NEW DERIVATIVES OF ERYTHROMYCIN, METHOD FOR THEIR PREPARING AND USING AS DRUGS Russian patent published in 2004 - IPC

Abstract RU 2237672 C2

FIELD: organic chemistry, chemical technology, antibiotics.

SUBSTANCE: invention relates to derivatives of erythromycin of the formula (I):

wherein Y means hydrogen or fluorine atom; n means a whole number from 1 to 8; Z means hydrogen atom or carboxylic acid residue and wherein pyrazole cycle is substituted with heteroaryl radical comprising one nitrogen atom, and also to their salt adducts with acids. Compounds of the formula (I) elicit antibiotic properties. Also, invention relates to a method for preparing compounds of the formula (I), pharmaceutical composition comprising thereof and intermediate compounds used for their preparing.

EFFECT: improved preparing method, valuable properties of derivatives and composition.

12 cl, 5 ex

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RU 2 237 672 C2

Authors

Deni Aleksis

Dates

2004-10-10—Published

1999-11-23—Filed