FIELD: medicine. SUBSTANCE: described are new erythromycin derivatives of general formula I: 
, wherein R and Z are as defined in claim 1, which show properties of antibiotics. Compounds are useful as medicinals for treating infections with sensitive microbes, more particularly staphylococcus infections e. g. staphylococcus sepsis, or the like. Also described are method of preparation thereof, pharmaceutical compositions based thereon and intermediate compounds. EFFECT: enhanced efficiency. 17 cl, 44 ex, 1 tbl
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1995 |
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