N-(BIPHENYLMETHYL)AMINOBENZOIC ACID ESTERS AND METHOD OF THEIR SYNTHESIS Russian patent published in 2000 - IPC

FIELD: organic chemistry and technology. SUBSTANCE: invention proposes N-(biphenylmethyl)aminobenzoic acid esters of the general formula: where R² means lower (C₁-C₄)-alkoxy-carbonyl group; R³ means lower (C₁-C₄)-alkoxycarbonyl group or -CN; Q² means -NO₂ or -NH₂ when Q¹ means H or Q² means -NO₂ when Q¹ means -COOR where R means lower (C₁-C₄)-alkyl, or salt of this compound. For synthesis of indicated compounds the corresponding carbamic acid ester is subjected for alkylation with an alkylating agent containing halogen atom followed by if necessary the protective group removal and the following optional reduction of the group -NQ¹ to NH-group. Indicated compounds can be used as intermediate substances for synthesis of benzimidazole derivatives that are used for drug synthesis. EFFECT: improved method of synthesis. 3 cl, 1 tbl, 16 ex