SUBSTITUTED CARBOCYCLIC AMIDES, METHODS OF PREPARATION THEREOF, INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS OF PROPHYLAXIS OR MEDICAL TREATMENT Russian patent published in 2000 - IPC

FIELD: medicine. SUBSTANCE: described are compounds of formula I wherein R₁ and R₂ are independently selected from chlorine, fluorine, bromine, C₁-C₆-alkyl, C₁-C₆-alkoxyl of C₁-C₆- haloalkyl provided that both R₁ and R₂ are not fluorine, R₃ and R₄ are selected from hydrogen and C₁-C₂-alkyl, and pharmaceutically acceptable salts, solvates thereof or physiologically, functional derivatives having antiphlogistic or analgesic activity, use thereof in medicine, especially for prophylaxis or medical treatment of states associated with inflammation, arthritis or pain, pharmaceutical compositions incorporated said derivatives, and methods of preparation thereof. EFFECT: improved properties of the pharmaceutical composition. 15 cl