1,4-BENZOTHIAZEPINE-1,1-DIOXIDE, PHARMACEUTICAL COMPOSITION DECREASING BLOOD LIPID LEVEL, METHOD OF TREATMENT OF MAMMAL CLINICAL STATE, METHOD OF SYNTHESIS OF COMPOUND Russian patent published in 2000 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to the novel 1,4-benzodiazepine-1,1-dioxides of the formula (II) where R¹, R² mean direct chain C_1-6-alkyl groups; R⁴ means unsubstituted phenyl; R⁵, R⁸ mean hydrogen atom; R⁶ means methoxy-group or bromine atom; R^7a means methoxy-, hydroxy- or trifluoromethyl-group; R⁹, R¹⁰ means hydrogen atom, and to salts, solvates or physiologically functional derivatives, and to method of their synthesis also. Except for, invention describes pharmaceutical composition based on indicated compounds that decreases blood lipid level and method of treatment of mammal clinical state. Invention can be used in medicine, in part, for prophylaxis and treatment of patients with hyperlipidemic states as atherosclerosis. EFFECT: improved method of synthesis, enhanced effectiveness of treatment and prophylaxis. 9 cl, 1 tbl, 53 ex