FIELD: medicine, virology. SUBSTANCE: invention proposes method of treatment of patients with HBV-infection that involves administration of effective amount of pure enantiomer of β-D-dioxolanylpurine nucleoside of the formula (I): 
where R is OH, Cl, NH2 or H; X is taken among the group including alkyl, acyl, monophosphate, diphosphate and triphosphate. Method results to inhibition of DNA replication of HBV-virions. EFFECT: improved method of treatment, valuable properties of agent. 25 cl, 3 tbl, 6 dwg, 7 ex
| Title |
Year |
Author |
Number |
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|
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|
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|
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|
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|
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|
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|
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|
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