FIELD: molecular biology. SUBSTANCE: invention relates to the novel growth/differentiation factor of TGF-β-family and coding its DNA sequences. Invention involves mature protein site and if necessary other functional regions of nucleotide sequence indicated in SEQ ID NO,1, vector containing copy of DNA molecule by p. 1, cell-host transformed by DNA by p. 1, protein expressed by other cells, method of its preparing, pharmaceutical compositions including this protein and polyclonal antibodies raised to this protein. Invention ensures to obtain DNA sequences that encode the novel members of proteins of TGF-β-family showing osteogenic properties. EFFECT: new factor indicated above, improved method of preparing, valuable medicinal properties. 9 cl, 3 tbl, 2 dwg
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