FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of phenylcyclohexylcarboxylic acid amide of the general formula (I) 
where D is the group -CH- or nitrogen atom; R1 is phenyl, cycloalkyl with 3-6 carbon atoms, direct or branched alkyl with 1-5 carbon atoms; R2 is direct or branched alkoxycarbonyl with 1-5 carbon atoms or residue of the formula -CO-NH2 or -CH2--OH, mixture of their isomers or separate isomers and their salts. Invention relates to also pharmaceutical composition based on compounds indicated above showing antiarteriosclerotic and antirestenosis activities. EFFECT: valuable medicinal properties of compounds. 5 cl, 3 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DERIVATIVES OF 2-PHENYLINDOLE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION SHOWING ANTIPROLIFERATIVE ACTIVITY | 1996 |
|
RU2162842C2 |
| DERIVATIVES OF CYCLOALKANOINDOLE AND AZAINDOLE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, DERIVATIVES OF CARBOXYLIC ACID AS PARENT COMPOUNDS AND PHARMACEUTICAL COMPOSITION INHIBITING RELEASE OF LIPOPROTEINS ASSOCIATED WITH APOLIPOPROTEIN B-100 | 1995 |
|
RU2157803C2 |
| DERIVATIVES OF HETEROCYCLE-SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR SALTS | 1994 |
|
RU2125990C1 |
| DERIVATIVES OF HETEROCYCLE-SUBSTITUTED PHENYLCYCLOHEXANECARBOXYLIC ACID, MIXTURE OR THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS | 1994 |
|
RU2119480C1 |
| DERIVATIVES OF CYCLOHEXADIENE, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND THEIR SALTS AND PHARMACEUTICAL COMPOSITION WITH SELECTIVE MODULATING EFFECT ON CALCIUM-DEPENDENT POTASSIUM CHANNELS OF HIGH CONDUCTIVITY | 1995 |
|
RU2155748C2 |
| DERIVATIVES OF BENZOFURANYLALKANE CARBOXYLIC ACID OR A MIXTURE OF THEIR ISOMERS, OR SEPARATE ISOMERS, OR THEIR SALTS | 1994 |
|
RU2125564C1 |
| DERIVATIVES OF PYRIDONE BIPHENYL AND THEIR SALTS | 1993 |
|
RU2118956C1 |
| N-(3-BENZOFURANYL)UREA DERIVATIVES, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS | 1996 |
|
RU2162845C2 |
| DERIVATIVES OF QUINOLINE-2-YL-METHOXYBENZYLHYDROXYUREA, METHOD OF SYNTHESIS AND 4-(QUINOLINE-2-YL-METHOXY)PHENYL-CYCLOALKYLKETONE AS A PARENTAL COMPOUND FOR SYNTHESIS OF QUINOLINE-2-YL-METHOXYBENZYLHYDROXYUREA DERIVATIVES | 1992 |
|
RU2048466C1 |
| CYCLOHEXANE IMIDAZOLYL SUBSTITUTED DERIVATIVES OR SALTS THEREOF | 1993 |
|
RU2110514C1 |
