MUTANT GP 50 FOR VECTOR VACCINE PREPARING, VECTOR VACCINE ANDMUTANT GP 50 FOR VECTOR VACCINE PREPARING, VECTOR VACCINE AND METHOD OF ITS PRODUCING Russian patent published in 2000 - IPC

FIELD: virology, veterinary science. SUBSTANCE: invention provides preparing vaccine for prophylaxisand control of diseases in animals including pseudorabies virus. Vaccine is useful against Aujeszky's diseases (pseudorabies) and other diseases in animals if mutation is the insertion that contains heterologous gene encoding antigen corresponding to this animal disease. Pseudorabies virus can carry additionally at least a single mutation in one of its other genes, for example, gene gp 63 or gene g1. This virus can not transferred from vaccinated to nonvaccinated animals. Attenuated virus can be administrated by intranasal route that provides the most effective prophylaxis of animal. EFFECT: mutant indicated above, enhanced effectiveness of vaccine. 4 cl, 3 tbl, 3 dwg, 6 ex