FIELD: medicine. SUBSTANCE: described are new 1-methylcarbopenem derivatives of general formula I: 
1-methylcarbapenem derivative is prepared by reacting compound II: 
with mercaptopyrrolidine derivatives of formula III: 
. Said compounds have antibacterial activity and are useful for preparing antibacterial agents intended for antibacterial effect. EFFECT: improved properties of the pharmaceutical composition. 11 cl, 145 ex, 6 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 1-METHYLCARBAPENEM OR ITS PHARMACOLOGICALLY ACCEPTABLE SALTS, COMPOSITION, METHOD OF PROPHYLAXIS OR TREATMENT OF PATIENT WITH BACTERIAL INFECTION | 1997 |
|
RU2162088C2 |
| CRYSTALLINE DERIVATIVES OF 1-METHYLCARBAPENEM | 2000 |
|
RU2214411C2 |
| CARBOPENEM DERIVATIVES AND A METHOD OF THEIR SYNTHESIS | 1993 |
|
RU2097383C1 |
| PEPTIDE COMPOUNDS AND METHOD OF PREPARING THEREOF | 1993 |
|
RU2106357C1 |
| 1-METHYLCARBAPENAM DERIVATIVES | 2001 |
|
RU2247725C2 |
| ACYLATED HETEROALICYCLIC DERIVATIVES, MEDICINAL AGENT SHOWING SELECTIVE ANTAGONISTIC ACTIVITY AGAINST NK-RECEPTORS, METHOD OF PROPHYLAXIS OR TREATMENT OF PATIENTS | 1998 |
|
RU2174122C1 |
| METHOD OF PRODUCING CARBAPENEM DERIVATIVES OR THEIR 4-NITROBENZYL ESTERS | 0 |
|
SU1501922A3 |
| DERIVATIVES OF CARBAPENEM, THEIR USING FOR PREPARING PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR TREATMENT AND/OR PROPHYLAXIS OF INFECTIOUS DISEASES | 2001 |
|
RU2276154C2 |
| DERIVATIVES OF NEURAMINIC ACID, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT AND PROPHYLAXIS OF INFLUENZA | 1997 |
|
RU2169145C2 |
| TRI- OR TETPA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVES | 2006 |
|
RU2420524C2 |
