FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to novel crystalline forms of derivative of 1-methylcarbapenem of the formula (I) or to its pharmaceutically acceptable salts that show antibiotonic activity against different bacterial strains in combination with sufficient stability for practice using. Invention relates also to pharmaceutical composition based on thereof and method for prophylaxis and treatment of bacterial diseases. EFFECT: enhanced stability at storage. 8 cl, 4 dwg, 5 tbl
Title |
Year |
Author |
Number |
1-METHYLCARBAPENEM OR ITS PHARMACOLOGICALLY ACCEPTABLE SALTS, COMPOSITION, METHOD OF PROPHYLAXIS OR TREATMENT OF PATIENT WITH BACTERIAL INFECTION |
1997 |
- Kavamoto Isao
- Isikava Katsuja
- Kodzima Katsukhiko
- Simodzi Jasuo
- Okh'Ja Satosi
- Morimoto Munetsugu
|
RU2162088C2 |
CARBOPENEM DERIVATIVES AND A METHOD OF THEIR SYNTHESIS |
1993 |
- Isao Kavamoto[Jp]
- Rokiro Ehndo[Jp]
- Masao Mijauti[Jp]
- Katsuja Isikava[Jp]
- Katsukhiko Vatanabe[Jp]
- Khirosi Jasuda[Jp]
- Satosi Okhija[Jp]
- Jukio Utsui[Jp]
|
RU2097383C1 |
1-METHYLCARBAPENEM DERIVATIVES, METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON, AND METHOD OF ANTIBACTERIAL EFFECT |
1996 |
- Isao Kavamoto
- Jasuo Simodzi
- Katsuja Isikava
- Katsukhiko Kodzima
- Khirosi Jasuda
- Satosi Okhja
- Jukio Utsui
|
RU2160737C2 |
CRYSTALLINE PIVALOYLHYDROXYMETHYL-(1R, 5S, 6S)-[(4R)-2-OXO-4--PYRROLIDINYLTHIO]-6-[(1R)-1-HYDROXYETHYL]-1-METHYL-1-CARBAPE--NE-2-EME-3-CARBOXYLATE AND METHOD OF ITS SYNTHESIS |
1993 |
- Isao Kavamoto[Jp]
- Masao Mijauti[Jp]
- Rokuro Ehndo[Jp]
|
RU2090567C1 |
USE OF DERIVATIVES OF 1-METHYLCARBOPENEM SHOWING ANTIBACTERIAL EFFECT WITH RESPECT TO HELICOBACTER PYLORI, COMPOSITION CONTAINING 1-METHYLCARBOPENEM DERIVATIVES AS ACTIVE COMPONENT AND METHOD OF PROPHYLAXIS AND TREATMENT OF INFECTIOUS DISEASE |
1997 |
- Kavamoto Isao
- Okh'Ja Satosi
- Utsui Jukio
|
RU2173147C2 |
METHOD OF PRODUCING CARBAPENEM DERIVATIVES OR THEIR 4-NITROBENZYL ESTERS |
0 |
- Yukio Sugimura
- Tosikhiko Khasimoto
- Teruo Tanaka
- Kimio Iino
- Tomoyuki Sibata
- Masayuki Ivata
|
SU1501922A3 |
1-METHYLCARBAPENEM DERIVATIVES AND METHOD OF PREPARATION THEREOF |
1992 |
- Isao Kavamoto[Jp]
- Rokuro Indo[Jp]
- Masao Mijjauti[Jp]
- Katsukhiko Vatanabe[Jp]
- Ejdzi Nakajama[Jp]
- Khirosi Jasuda[Jp]
- Satosi Okhia[Jp]
- Jukio Utsui[Jp]
|
RU2093514C1 |
1-METHYLCARBAPENAM DERIVATIVES |
2001 |
- Kobajasi Josijuki
- Sinozuka Tsujosi
- Kanno Osamu
|
RU2247725C2 |
CARBAPENEM DERIVATIVE, ANTIBACTERIAL AGENT BASED ON IT, AND ITS INTERMEDIATE |
1998 |
- Matsui Khirosi
- Kasai Masajasu
|
RU2178792C2 |
DERIVATIVES OF CARBAPENEM, THEIR USING AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING |
1999 |
|
RU2222540C2 |