METHOD OF TREATMENT OF PATIENTS WITH FEAR STATE OR TREATMENT AND/OR PROPHYLAXIS OF PANIC STATE, PURIFIED PROTEIN ABLE TO BIND GABAPENTIN AND PHARMACEUTICAL COMPOSITION SHOWING SEDATIVE, ANTIPANIC AND ANTICONVULSANT EFFECTS Russian patent published in 2001 - IPC

FIELD: medicine. SUBSTANCE: method involves administration of gabapentin or its pharmaceutically acceptable salt to patient in the dose 5-50 mg by parenteral route or in the dose 50-600 mg by enteral route. Gabapentin can be in form of active compound showing sedative, antipanic and anticonvulsant effect in pharmaceutical composition able to interact with protein binding [³H]-gabapentin, in part, to interaction with purified protein exhibiting the sequence of the first ten amino acid residues EPFPSAVTIK that are the sequence of α₂-delta-subunit of Ca²⁺-channel. EFFECT: broadened arsenal of methods and agents used for prophylaxis and treatment of patients with fear and panic states. 4 cl, 5 dwg