COMPOUNDS WITH CAMPTOTHECIN STRUCTURE, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITIONS Russian patent published in 2001 - IPC

Abstract RU 2169149 C2

FIELD: natural organic compounds. SUBSTANCE: invention relates to novel alkaloids of the formula (I) occurring in different parts of plant Mappia foetida and their pharmaceutical use as novel syntones for synthesis of compounds with antitumor and antiviral activity. The same compounds are novel syntones for synthesis of new analogues of camptothecin and foetidins. Invention describes also method of synthesis of compounds of the formula (I). These new compounds show high water solubility that ensures their administration by parenteral route without conversion to derivatives. EFFECT: new alkaloids indicated above, valuable medicinal properties. 7 cl, 1 dwg, 4 ex

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RU 2 169 149 C2

Authors

Bombardelli Ehtsio

Verotta Luizella

Dates

2001-06-20Published

1997-05-02Filed