STEREOISOMERIC INDOLE COMPOUNDS, METHOD OF THEIR SYNTHESIS AND THEIR USING Russian patent published in 2002 - IPC

FIELD: organic chemistry, chemical technology, biochemistry. SUBSTANCE: invention discloses the novel stereoisomeric indole compounds of the formula (I) where Y, X, R₁,R₂ and R are characterized in description, method of their synthesis and using. The above indicated compounds can be synthesized by condensation of tryptophan with stereoisomeric α-amino acid or carboxylic acid to yield amide form and the following cyclization of amide form to form oxazolic ring. Compounds show physiological activity, for example, an inhibitory effect against lipid peroxidation and can be used as inhibitors of lipid peroxidation comprising the indicated active component. EFFECT: improved method of synthesis, valuable biochemical properties. 7 cl, 10 dwg, 2 tbl, 8 ex