FIELD: biotechnology, microbiology, virology. SUBSTANCE: strain of yeast Saccharomyces cerevisiae = 965 (GKV) shows high level of production of surface antigen of hepatitis B virus and its activity to the end of fermentation is 1/256 000 that exceeds activity of HBs Ag produced by the known strains by 10-fold. Invention can be used for preparing the recombinant surface antigen of hepatitis B virus (HBs Ag). EFFECT: increased yield of antigen production. 2 tbl, 1 ex
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Authors
Dates
2002-05-27—Published
2000-05-11—Filed