STRAIN OF HYBRID CELLS M/N-10G9 OF ANIMAL MUS MUSCULUS L PRODUCING MONOCLONAL ANTIBODIES RAISED TO MARBURG VIRUS Russian patent published in 2002 - IPC

Abstract RU 2186107 C1

FIELD: biotechnology, virology. SUBSTANCE: invention relates to hybridoma technology. Hybridoma is obtained by fusion of murine myeloma line NSO with murine splenocytes strain BALB/c immunized with inactivated Marburg virus. Hybridoma-produced monoclonal antibodies raised to Marburg virus (strain Popp) surface glycoprotein can be used as a component of IFA- system used for detection of Marburg virus. The resolution capacity of system based on monoclonal antibody is 1.0 x 103 PFU x cm-3. The use of hybridoma producing monoclonal antibody raised to Marburg virus ensures to carry out the detection and identification of this virus. EFFECT: hybrid cells indicated above, valuable properties. 1 dwg, 4 tbl, 1 ex

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RU 2 186 107 C1

Authors

Ruchko S.V.

Lebedev V.N.

Pashchenko Ju.I.

Borisevich G.V.

Firsova I.V.

Khamitov R.A.

Maksimov V.A.

Dates

2002-07-27Published

2001-03-29Filed