FIELD: biotechnology, immunology. SUBSTANCE: invention relates to hybridoma technology. Hybridoma is obtained by fusion of murine myeloma line NSO and murine splenocytes line BALB/c immunized with inactivated Ebol's virus. Hybridoma produces monoclonal antibodies isotype IgG to Ebol's virus used as a component of IFA-system for indication and identification of Ebol's virus. The resolution capacity of test-system based on monoclonal antibody is estimated to be 1.0 x 103 PFU x cm-3. The use of hybridoma provides to obtain monoclonal antibodies raised to GP protein of Ebol's virus. EFFECT: hybridoma indicated above, valuable properties. 1 dwg, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN OF HYBRID CELLS M/N-10G9 OF ANIMAL MUS MUSCULUS L PRODUCING MONOCLONAL ANTIBODIES RAISED TO MARBURG VIRUS | 2001 |
|
RU2186107C1 |
| STRAIN OF HYBRID CELLS R1/S-5A6 OF ANIMALS MUS MUSCULUS L PRODUCING MONOCLONAL ANTIBODY RAISED TO RICKETTSIA PROWAZEKII | 2001 |
|
RU2198922C2 |
| STRAIN OF T2/S-6E11 HYBRID CELLS OF ANIMAL MUS MUSCULUS L. PRODUCING MONOCLONAL ANTIBODIES RAISED TO CORONAVIRUS AS PATHOGEN OF SEVERE ACUTE RESPIRATORY SYNDROME | 2005 |
|
RU2291195C1 |
| STRAINS OF HYBRID CELLS OF ANIMALS MUS_ MUSCULUS - PRODUCERS OF MONOCLONAL ANTIBODIES TO PROTEIN GP OF EBOLA VIRUS (SUBTYPE ZAIRE) AND MONOCLONAL ANTIBODIES TO PROTEIN GP OF EBOLA VIRUS (SUBTYPE ZAIRE) | 2017 |
|
RU2686630C1 |
| STRAIN OF MAMMALIAN HYBRID CELL C3/S-3E5 OF MUS MUSCULUS L. PRODUCING MONOCLONAL ANTIBODY TO BERNET'S COXIELLAS | 2003 |
|
RU2257414C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) | 2008 |
|
RU2395577C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus MUSCULUS 1F1 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE NUCLEOCAPSID PROTEIN N OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2769817C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus museums L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) | 2008 |
|
RU2395576C1 |
| STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS 2E1B5 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE RECEPROT-BINDING DOMAIN OF PROTEIN S OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2771288C1 |
| STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS L3F9 - PRODUCER OF MONOCLONAL ANTIBODIES SUITABLE FOR USE IN "SANDWITCH" IMMUNOENZYMOMETRIC SYSTEM FORMAT FOR DETECTING VP35 PROTEIN OF MARBURG VIRUS AND 3F9 MONOCLONAL ANTIBODIES PRODUCED BY SAID STRAIN OF HYBRID CELLS | 2008 |
|
RU2393220C1 |
