FIELD: biotechnology.
SUBSTANCE: invention refers to biotechnology and molecular biology. Disclosed is a method for assessing the ability of a candidate molecule to inhibit a covalently closed ring (ccr) DNA of hepadnavirus, which is hepatitis B virus (HBV).
EFFECT: method provides reliable screening of hepatitis B virus inhibitors that can be used in medicine.
19 cl, 13 dwg, 1 ex
| Title |
Year |
Author |
Number |
| SYSTEM FOR ACTIVATING HUMAN APOBEC/AID CYTIDINE DEAMINASES AND/OR HUMAN URACIL-DNA-GLYCOSYLASE UNG AND ITS USE FOR ELIMINATING CCC DNA OF HEPATITIS B VIRUS FROM HUMAN CELLS, PARTICULARLY HEPATOCYTES |
2018 |
- Kostyushev Dmitrij Sergeevich
- Kostyusheva Anastasiya Pavlovna
- Zarifyan Dmitrij Nikolaevich
- Brezgin Sergej Alekseevich
- Chulanov Vladimir Petrovich
|
RU2703532C1 |
| MUTANT POLYMERASES OF HEPATITIS B VIRUS |
2012 |
- Marten Perrin
- Silvestr Natali
- Marshan Zhan-Baptist
|
RU2625021C2 |
| RNA-CONDUCTORS TO SUPPRESS THE REPLICATION OF HEPATITIS B VIRUS AND FOR THE ELIMINATION OF HEPATITIS B VIRUS FROM HOST CELL |
2017 |
- Kostyushev Dmitrij Sergeevich
- Kostyusheva Anastasiya Pavlovna
- Zarifyan Dmitrij Nikolaevich
- Brezgin Sergej Alekseevich
- Chulanov Vladimir Petrovich
|
RU2652899C1 |
| BISPECIFIC BINDING AGENTS WITH INTERSPECIFIC SPECIFICITY |
2008 |
- Klinger,Matthias
- Raum,Tobias
- Rau,Doris
- Mangold,Susanne
- Kischel,Roman
- Lutterbuse,Ralf
- Hoffmann,Patrick
- Kufer,Peter
|
RU2535992C2 |
| VASCULAR ADHESION PROTEIN-1 OF AMINOOXIDASE ACTIVITY |
1998 |
- Jalkanen Sirpa
- Salmi Marko
- Smit Dehjvid Dzhon
- Bono Petri
|
RU2204838C2 |
| BACTERIAL VIRULENCE FACTORS AND VERSIONS FOR APPLYING IT |
2004 |
- Finlej Brett
- Grjunkhejd Samanta
- Dehn Van'In'
- Vallans Brjus
- Puehnte Khose L.
|
RU2465331C2 |
| RNA-CONDUCTOR St10 FOR USE IN THE HIGHLY SPECIFIC STREPTOCOCCUS THERMOPHILUS CRISPR / Cas9 (StCas9) NUCLEASES SYSTEM AND USE OF SAID RNA-CONDUCTOR AND StCas9 PROTEIN TO SUPPRESS HEPATITIS B VIRUS EXPRESSION IN THE HOST CELL AND FOR VIRAL DNA ELIMINATION FROM THE HOST CELL |
2018 |
- Kostyushev Dmitrij Sergeevich
- Kostyusheva Anastasiya Pavlovna
- Chulanov Vladimir Petrovich
- Chulanov Vladimir Petrovich
|
RU2694396C1 |
| RECOVERED PEPTIDE EXHIBITING SPECIFIC ANTI-GDF-8 ANTIBODY BINDING ACTIVITY, RECOVERED NUCLEIC ACID MOLECULE, EXPRESSION VECTOR, HOST CELL, METHOD FOR PRODUCING PEPTIDE, VACCINE COMPOSITION AND METHOD OF ELICITING ANTI-GDF-8 IMMUNE RESPONSE, METHOD OF ANTI-GDF-8 ANTIBODY SELECTION SCREENING AND METHOD OF GDF-8 ACTIVITY DOWN-REGULATION IN ANIMAL |
2004 |
- Dzhanker Dehvid Eh.
- Kokhrehn Mark D.
|
RU2422460C2 |
| VIRAL VECTOR MANUFACTURE |
2014 |
|
RU2658487C2 |
| IMMUNOGENIC COMPOSITIONS FOR IMMUNIZATION OF PIGS AGAINST CIRCOVIRUS TYPE 3 AND METHODS OF PRDUCTION AND APPLICATION THEREOF |
2016 |
|
RU2744193C2 |
