FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to salts of sulfoxide derivatives, namely to: 1-{2-[(2R)-(3,4-dichloro-phenyl)-4-(3,4,5-trimethoxybenzoyl)morpholine-2-yl] ethyl} spiro-[benzo(c)thiophene-1(3H)-4'-piperidine]-(2S)-oxide hydrochloride or fumarate that show good absorption in oral intake and show the excellent antagonistic activity with respect to both NK1-receptors and NK2-receptors. EFFECT: valuable medicinal properties of compounds. 23 cl, 3 tbl, 33 ex
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2001 |
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