BENZOXAZINE OR PYRIDOOXAZINE COMPOUNDS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS SHOWING ANTIBACTERIAL ACTIVITY, METHODS OF TREATMENT OF BACTERIAL INFECTIONS Russian patent published in 2002 - IPC

Abstract RU 2191179 C2

FIELD: organic chemistry, chemical technology, medicine, pharmacy. SUBSTANCE: invention relates to novel benzoxazine and pyridooxazine compounds of the formula (1) where a moiety Q means a condensed phenyl or condensed pyridyl; Z1 means hydrogen, halogen atom, C1-C6-alkyl, phenyl, nitro-group, sulfonylamino-group or trifluoromethyl-group; Z2 means hydrogen or halogen atom; X means hydrogen or oxygen atom; A means C1-C6-alkyl, C1-C6-alkylaryl or C1-C6- alkylheterocyclyl where aryl and heterocyclyl are described in the invention claim; n is a whole number from 0 to 3; Y means a moiety described in the invention claim, and to their pharmaceutically acceptable salts, esters and promedicinal forms. Invention discloses also methods of their synthesis, intermediate compounds, pharmaceutical compositions based on thereof showing an antibacterial activity and to methods of treatment of bacterial infections. Invention can be used in medicine as anti-infectious agents. EFFECT: new compounds indicated above, improved methods of synthesis and treatment, valuable medicinal property. 32 cl, 2 tbl

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RU 2 191 179 C2

Authors

Frechett Rodzher

Vejdner-Vellz Majkl A.

Dates

2002-10-20Published

1996-10-17Filed