METHOD OF IMMUNOGLOBULIN PREPARATION PREPARING Russian patent published in 2002 - IPC

FIELD: medicine, immunology. SUBSTANCE: method involves dissolving alcohol fraction of blood plasma containing immunoglobulins in water or buffer solution, bringing up protein concentration to 0.5-20.0% and pH value to 3.5-5.0, acid addition at temperature 0-20 C, ultrafiltration, diafiltration, dialysis, maltose addition and sterilizing filtration. Water-soluble blood plasma alcohol fraction in protein concentration 0.1-8.0% is brought about to pH value 6.5-7.8, incubated at temperature +4 C - +20 C, precipitate is removed by centrifugation or filtration and aluminum hydroxide is added in the amount 10/40 ml per 1 l of solution followed by incubation for 3-5 h at the room temperature and aluminum hydroxide is separated by centrifugation. Invention can be used for immunotherapy and immunoprophylaxis of bacterial and viral diseases. Method provides removal of impurities of proteins, lipids and viruses. EFFECT: improved method of preparing, enhanced quality of preparation. 1 tbl, 2 ex