NOVEL DERIVATIVES OF ASPARTYL DIPEPTIDE ESTER AND SWEETENING AGENTS Russian patent published in 2002 - IPC

FIELD: organic chemistry, food industry. SUBSTANCE: invention proposes novel derivatives of aspartyl dipeptide ester (including their salts) presented by the formula (I) where each among R₁, R₂, R₃, R₄, R₅ means independently each of other substitute taken among hydrogen atom (H), hydroxyl group (OH), alkoxy-group (OCH₃, OCH₂CH₃, OCH₂CH₂CH₃ and so on) with 1-3 carbon atoms, alkyl group (CH₃, CH₂CH₃, CH₂CH₂CH₃ and so on) with 1-3 carbon atoms; R₆ means substitute taken among hydrogen atom, benzyl group (CH₂C₆H₅), cyclohexylmethyl group (CH₂C₆H₁₁), phenyl group (C₆H₅), cyclohexyl group (C₆H₁₁), phenylethyl group (CH₂CH₂C₆H₅) and cyclohexylethyl group (CH₂CH₂C₆H₁₁); R₇ means substitute taken among hydrogen atom, methyl group (CH₃), ethyl group (CH₂CH₃) and isopropyl group (CH(CH₃)₂); R₈ means substitute taken among methyl group, ethyl group, isopropyl group, n-propyl group (CH₂CH₂CH₃) and tert.-butyl group (C(CH₃)₃) under condition that derivatives comprising benzyl group as R₆ and with hydrogen atom as R₇ as well as p-hydroxybenzyl group as R₆ with hydrogen atom as R₇ are excluded. Compounds show high sweetening capacity and enhanced stability to hydrolysis. Invention proposes also sweetening agent comprising compounds based on invention proposed. EFFECT: valuable properties of compounds. 15 cl, 1 tbl, 14 ex