BENZOTHIAZOLE DERIVATIVE OR ITS PHARMACOLOGICALLY ACCEPTABLE SALT Russian patent published in 1995 - IPC

Abstract RU 2041216 C1

FIELD: organic chemistry. SUBSTANCE: product: derivatives of benzothiazole of the formula: (bond with sulfur) -CR1=C(OR2)-CR3-CR4-C- (bond with nitrogen)= -S-C/NR5R6/N-/ N where R1 and R2 are similar or different hydrogen, lower alkyl or alkoxy-group or a group of the formula: -(CH2)p-Pr at p 1-4; R4 hydrogen, lower alkyl, phenyl or a group of the formula: -(CH2)q-Pr at q 1-4, or a group of the formula: -C(/O-C(O)-R7/H-Pr, R7 lower alkyl, or R3 and R4 form benzene ring together with carbon atoms with which they are bound; R2 hydrogen or lower alkyl; R5 and R6 are similar or different hydrogen or lower alkyl or a group of the formula: -(CH2)r-Pr at r 1-4; Pr pyridyl, or its pharmacologically acceptable salts. EFFECT: improved method of synthesis. 24 cl, 3 tbl

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Authors

Jasusi Okamoto[Jp]

Katsuja Tagami[Jp]

Sigeki Khibi[Jp]

Khirotosi Numata[Jp]

Naoki Kobajasi[Jp]

Masanobu Sinoda[Jp]

Tetsuja Kavakhara[Jp]

Manabu Murakami[Jp]

Kiesi Oketani[Jp]

Takasi Inoue[Jp]

Takasi Jamanaka[Jp]

Isao Jamatsu[Jp]

Dates

1995-08-09Published

1992-04-03Filed