FIELD: organic chemistry, medicine, cardiology, pharmacy. SUBSTANCE: invention describes compounds of the formula (I) and also their stereoisomers, acid-additive salts and hydrates where substituted have values given in description. Invention describes also preparing a pharmaceutical composition showing antiarrhythmic activity. Invention proposes also method of treatment of cardiac arrhythmia in mammals involving administration of antiarrhythmic amount of compound of the formula (I). EFFECT: improved method preparing, valuable medicinal properties. 6 cl, 2 dwg, 11 tbl, 39 ex
Title | Year | Author | Number |
---|---|---|---|
COMPOUNDS, METHOD FOR PREPARING COMPOUND, PHARMACEUTICAL COMPOSITION | 2000 |
|
RU2244709C2 |
DERIVATIVES OF PIPERIDINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND INTERMEDIATE COMPOUNDS | 1997 |
|
RU2193029C2 |
SYNTHESIS OF NOVEL CLASS OF FLUORINE-CONTAINING LIQUID-CRYSTALLINE COMPOUNDS WITH APPLICATION OF CHLADONE 114B2 AS INITIAL COMPOUND | 2012 |
|
RU2505529C1 |
COMPOUNDS WITH HYDROXYCARBONYL-HALOGENALKYL BY-SIDE CHAINS | 2000 |
|
RU2247106C2 |
5-AMINO-3-(2-AMINOPROPYL)-[1,2,4]THIADIAZOLES | 2011 |
|
RU2449997C1 |
1-(4-ISOXAZOLE-5-YL)-1H-PYRAZOLE-1-YL)-2-METHYLPROPANE-2-OL DERIVATIVES AND RELATED COMPOUNDS AS IL-17 AND IFN-GAMMA INHIBITORS FOR TREATMENT OF AUTOIMMUNE DISEASES AND CHRONIC INFLAMMATION | 2018 |
|
RU2785342C2 |
SUBSTITUTED HYDROXAMIC ACIDS, PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF AND METHOD OF TNF (TUMOR NECROSIS FACTOR) α DECREASE | 1998 |
|
RU2199530C2 |
DERIVATIVES OF PIPERAZINE, COMPOUNDS, PHARMACEUTICAL COMPOSITION | 1997 |
|
RU2179554C2 |
METHOD OF PRODUCING (1S,4R)-1-ISOPROPYL-4-METHYL-10-ARYL-7,8,12,13-TETRAOXA-10-AZASPIRO[5_7]TRIDECANES | 2019 |
|
RU2726405C1 |
SUBSTITUTED ISOXAZOLES, PHARMACEUTICAL COMPOSITIONS BASED THEREON HAVING ANTIVIRAL ACTIVITY, AND METHOD FOR USE THEREOF | 2018 |
|
RU2733945C2 |
Authors
Dates
2002-11-20—Published
1998-12-10—Filed