FIELD: medicine. SUBSTANCE: 4- amino-3-acylquinoline derivatives of general formula I:
wherein R1 and R3 are C1-6 alkyl; R2 is C1-6 alkyl, halogen, C1-6 alkoxy; R4 is H, C1-6 alkyl, halogen or OH, m is 2 or 3, n is integer of 0,1,2 or pharmaceutically acceptable salts thereof exogenically or endogenically inhibit stimulated secretion of gastric acid are useful for prophylaxis and treatment of inflammatory gastrointestinal diseases. EFFECT: improved properties of the pharmaceutical agent. 13 cl, 57 ex, 1 tbl
Title |
Year |
Author |
Number |
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