FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to dihydropyridines of the general formula (I) 
where R1,R2 - H, chlorine, bromine atom, cyano-group, CF3; R3,R4 - C1-5-alkyl including all optical isomers that are strong acting antagonists of calcium showing very short effect and high vascular selectivity and exhibiting the effectiveness for decrease of blood pressure. EFFECT: improved method of synthesis, valuable pharmacological properties. 9 cl, 1 tbl, 6 ex
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Year |
Author |
Number |
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1994 |
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1998 |
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RU2193036C2 |
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1997 |
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1994 |
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|
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